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Madhusudhana Rao A Anand U Anand CV 《Indian journal of clinical biochemistry : IJCB》2011,26(1):28-31
Numerous lines of evidence implicate a role of myeloperoxidase (MPO) in the pathogenesis of cardiovascular disease (CVD).
It is a well accepted fact that patients with chronic kidney disease (CKD) are at an increased risk for CVD. MPO is a pro-oxidant
enzyme which could be involved in the increased susceptibility of these patients to CVD. Hence, the levels of plasma MPO was
determined in healthy controls as well as in patients with CKD [stratified with the level of their kidney failure as CKD stages
II–V (end stage renal disease)]. Plasma MPO was assayed by a spectrophotometric method. Serum urea and creatinine were estimated
on a clinical chemistry analyzer using standard laboratory procedures. The mean plasma MPO levels were significantly lower
with advancing stages of renal failure (P < 0.001). There was a positive correlation between MPO and GFR (r = +0.89, P < 0.001) and a negative correlation with urea (r = −0.85, P < 0.001) and creatinine (r = −0.82, P < 0.001). While an inverse association was observed between plasma MPO and urea in CKD patients, such an association was
not observed in control subjects (P = 0.43). In conclusion, the decline in plasma MPO levels may be due to the inhibitory effect of uraemic toxins on the enzyme. 相似文献
44.
A. K. Pradhan A. K. Shukla M. V. R. Reddy N. Garg 《Indian journal of clinical biochemistry : IJCB》2004,19(1):83-87
Oxidative stress was assesed by estimating lipid peroxidation product (LPO) in the form of thiobarbituric acid reactive substances
(TBARS), enzymatic antioxidants in the form of superoxide dismutase (SOD), catalase and nonenzymatic antioxidant vitamins
e.g. vitamin C, β carotene and vitamin E in either serum or plasma or erythrocytes in 190 cases of age related cataract in
the age group of 50–80 years. 190 cases were grouped into three morphological types namely, 73 cases of cortical, 77 cases
of posterior subcapsular and 40 cases of nuclear cataract and values of LPO and antioxidants were compared with 78 cases of
age matched healthy control groups. Plasma TBARS levels were cataract cases when compared with control groups. There were
no significant differences in the erythrocyte levels of catalase and plasma levels of Vit E between cataract cases and control
groups. No significant changes of parameters were seen among three different morphological types of age related cataract.
The present study shows that the oxidative stress may play an important role in the age related cataract. 相似文献
45.
我国高校教师压力随着经济实力的增长,和教学改革的推进而不断增大,原因来自于社会、学校和自身各方面,本文主要通过与瑞典高校教师的压力的比较,吸取国外优秀的经验,解决我国对前存在的教师压力问题。 相似文献
46.
水分胁迫对黄淮海夏玉米农业气候资源利用的影响——水分胁迫对叶片生产力影响 总被引:2,自引:0,他引:2
文章对水分胁迫的夏玉米光合生产力变化进行了系统观测和实验 ,研究表明 :①可将土壤持水量的 4 0 6 89%~ 5 5 79%和 79 99%作为叶片缺水及最适的外部形态指标 ;②干旱可以使株高低 2 2 5 6 %左右 ,而短时间内水分一直维持在田间持水量水平 ,对玉米的株高影响并不大 ;③比叶重随土壤湿度增加而增大 ,到田间持水量的 79 9%时达到最大值 ,随着湿度的进一步增加 ,比叶重反而略微变小 ;④叶片含水量与土壤湿度成正相关 ,吸收辐射率则受叶片湿度与厚度的影响 ,当土壤湿度达到持水量的 79 99%时 ,叶片吸收辐射率可达到 80 %左右。在此研究基础上 ,给出了包含浓度、辐射强度、温度及土壤水分因子的夏玉米叶片生产力计算公式 ,为进一步准确推算水分胁迫对区域生产力的可能影响 ,为当地政府开发农业气候资源提供了前提条件。 相似文献
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M. Maneesh Sanjiba Dutta Amit Chakrabarti D M Vasudevan 《Indian journal of clinical biochemistry : IJCB》2007,22(1):138-142
Infertility is well-established harmful effect in chronic alcoholism and so far, there is no effective treatment for this
condition. The study was conducted to determine the effects of alpha tocopherol on ethanol induced testicular injuries in
male albino rats of Wistar strain. Five groups (n=6) of animals were used. Group I served as control. Group II received daily
1.6g ethanol/kg body weight/day for 4 weeks orally. Group III received 1.6g ethanol+80mg alpha tocopherol/kg body weight/day
for four weeks orally. Group IV received 1.6g ethanol/kg body weight for/day 4 weeks and followed by 80mg alpha tocopherol/kg
body weight/day for four weeks orally. Group V received 1.6g ethanol/kg body weight/day orally for 4 weeks, followed by 4
weeks abstinence. Twently-four hours after the last treatment the rats were sacrificed using anesthetic ether. Testes were
removed and used for the estimation of extent of lipid peroxidation and tissue levels of antioxidants and steroidogenic enzymes.
Alpha tocopherol treatment increased the activities of testicularΔ
5, 3β-HSD. Moreover, the treatment was also associated with significant decrease in testicular oxidative stress. Ethanol-induced
oxidative stress and decreased steroidogenesis can be reversed by treatment with alpha tocopherol. 相似文献
49.
企业文化创新与企业核心竞争力 总被引:1,自引:0,他引:1
21世纪企业之间的竞争,根本上是企业文化的竞争。随着知识经济的发展,创新企业文化对企业核心竞争力的提升将发挥越来越重要的作用。中国企业进入了新的发展阶段,需要企业文化再上新台阶与之匹配。企业文化的创新与发展是一个逐步探索、逐步深入的系统工程,面对加入世界竞争带来的机遇和挑战,我国企业也应审时度势,调整自身行为,重视企业文化建设。从基于企业文化创新力的“合力”入手,阐述了文化创新对企业核心竞争力的作用,旨在通过促进企业文化创新,提升企业的核心竞争力。 相似文献
50.
解梅香 《荆门职业技术学院学报》2011,(5):42-43
目的:探讨运动平板试验中护理配合的方法及对检查的影响。方法:对468例运动平板试验前、中、后的护理干预措施进行分析总结。结果:468例病人,运动试验阳性165例,其中发生心律失常65例、心绞痛27例、晕厥3例,经护理干预后,无休克、猝死等不良事件发生。结论:通过对运动平板试验的正确护理,能及时发现患者病情变化,有效地防止不良事件发生。 相似文献